Package: bridge
Description: Test for differentially expressed genes with microarray
data. This package can be used with both cDNA microarrays or
Affymetrix chip. The packge fits a robust Bayesian
hierarchical model for testing for differential expression.
Outliers are modeled explicitly using a $t$-distribution. The
model includes an exchangeable prior for the variances which
allow different variances for the genes but still shrink
extreme empirical variances. Our model can be used for testing
for differentially expressed genes among multiple samples, and
can distinguish between the different possible patterns of
differential expression when there are three or more samples.
Parameter estimation is carried out using a novel version of
Markov Chain Monte Carlo that is appropriate when the model
puts mass on subspaces of the full parameter space.
Version: 1.0.1
Author: Raphael Gottardo
Maintainer: Raphael Gottardo
Dependencies: R (>= 1.9.0), rama
Suggests: None
SystemRequirements: None
License: GPL version 2 or newer
URL: None available
Win32 package download