TAP complexes {apComplex}R Documentation

TAP data complex estimates

Description

Affiliation matrices with rows corresponding to proteins and columns corresponding to complexes.

Usage

data(MBMEcTAP)
data(SBMHcTAP)
data(UnRBBcTAP)

Details

These are the results from an analysis of the TAP data (Gavin et al., 2002) using the Protein Complex Membership Graph (PCMG) algorithm proposed by Scholtens and Gentleman (2004). These estimates were constructed using a sensitivity parameter of .75, specificity of .995, and external data based on Gene Ontology cellular component annotation.

MBMEcTAP contains multi-bait-multi-edge complex estimates. SBMHcTAP contains single-bait-multi-hit complex estimates. UnRBBcTAP contains unreciprocated bait-bait complex estimates.

Source

Scholtens, D. and Gentleman, R. Making sense of high throughput protein-protein interaction data. (2004).

References

Gavin, et al. Functional organization of the yeast proteome by systematic analysis of protein complexes. Nature 415, 141-147 (2002).

Examples

data(MBMEcTAP)


[Package apComplex version 1.0.1 Index]