mergeFunc {aCGH}R Documentation

Funtion to merge states based on their state means

Description

This function takes an output of hmm.run.fun (states.hmm) with a particular model selection criterion andietratively merges the states which means are closer than a supplied threshold.

Usage

mergeFunc(statesres = states.bic, minDiff = 0.1)

Arguments

statesres the sublist of the states.hmm list output from find.hmm.states for a given model selection crterion
minDiff The states whose predicted values are less than minDiff apart are merged into one state and all the predicited values are recomputed

Details

This function is intended to reduce effect of the possible small magnitude technological artifcats on the structure determination.

Value

List containing states.hmm object is returned.

Author(s)

Jane Fridlyand

References

Application of Hidden Markov Models to the analysis of the array CGH data, Fridlyand et.al., JMVA, 2004


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