diffVar {RnBeads} | R Documentation |
This routine applies the diffVar method from the missMethyl
package that determines sites exhibiting
differential variability between two sample groups
diffVar(meth.matrix, inds.g1, inds.g2, adjustment.table = NULL, paired = FALSE)
meth.matrix |
Matrix containing the methylation information used to calculate differentially variable sites between the two groups |
inds.g1 |
Indices in the phenotypic table corresponding to the first group. |
inds.g2 |
Indices in the phenotypic table corresponding to the second group. |
adjustment.table |
A |
paired |
Should the analysis be performed in a paired fashion. If yes, the first index in |
P-values as the result of the diffVar method not adjusted for multiple hypothesis testing.
Michael Scherer
Phipson, Belinda, Oshlack, Alicia (2014) DiffVar: a new method for detecting differential variability with application to methylation in cancer and aging Genome Biology 15(9):465.